A major new study finds that structured exercise can significantly reduce colon cancer recurrence and improve survival rates in high-risk patients.
Survival Rates Improve with Movement
A groundbreaking international study published Sunday in the New England Journal of Medicine shows that regular, structured exercise can significantly improve survival rates for patients with colon cancer. Over a 15-year trial, patients who engaged in moderate exercise three times a week had a 90% survival rate seven years after diagnosis—compared to 83% for those given only standard health advice.
Global Trial Spans Three Countries
The clinical trial enrolled 889 colon cancer patients from 55 hospitals across Canada, Australia, and the United Kingdom. Participants had high-risk stage 2 or stage 3 colon cancer and had already undergone surgery and chemotherapy. Researchers divided them into two groups: one received an exercise pamphlet; the other was guided through a structured, three-year physical activity program.
A Flexible but Committed Exercise Routine
Patients in the structured group were free to choose their activity—be it walking, biking, swimming, or gym workouts—but were required to maintain an elevated heart rate for 30 to 45 minutes, three times a week. Monthly check-ins with trainers or physiotherapists ensured adherence. For Edmonton resident James Smith, a colon cancer survivor, the program included brisk treadmill walks that became a source of empowerment during his recovery.
More Than Just a Fitness Benefit
While participants did not show major changes in weight or cardiovascular health, those in the exercise group had lower recurrence rates: 80% remained cancer-free five years after diagnosis versus 74% in the pamphlet-only group. Researchers emphasize that exercise isn’t a replacement for chemotherapy, but it significantly boosts its effectiveness.
Comparable to Chemotherapy, Experts Say
Dr. Chris Booth, oncologist and study co-author from Queen’s University, noted that the benefits of structured exercise rival some chemotherapy drugs in terms of impact. Meanwhile, Toronto-based colorectal surgeon Dr. Sami Chadi, who was not involved in the study, now considers exercise a post-treatment must. “We should be recommending it as strongly as chemotherapy,” he said.
Still Searching for the ‘Why’
The exact biological mechanism behind exercise’s impact on cancer remains unclear. Researchers collected blood samples throughout the trial and plan to study biomarkers to understand how physical activity reduces cancer recurrence. Despite the mystery, the results are already shifting clinical perspectives.
A Personal Victory in the Data
For Smith, who lost 26 kilograms during treatment, the exercise program not only aided physical recovery but helped reclaim a sense of control. Now cancer-free and back to playing hockey, he credits the program with improving both his health and peace of mind. “It gives me extra reassurance that what I’m doing is helping keep the cancer away.”
Policy Implications on the Horizon
Lead researcher Kerry Courneya of the University of Alberta hopes the data prompts healthcare systems to invest in structured post-treatment fitness programs. With colon cancer among the most common cancers worldwide, the study may lead to policy changes that integrate exercise as a formal part of cancer care.